2021

1. Hioki T, Tokuda H, Nakashima D, Fujita K, Kawabata T, Sakai G, Kim W, Tachi J, Tanabe K, Matsushima-Nishiwaki R, Otsuka T, Iida H and Kozawa O.
HSP90 inhibitors strengthen extracellular ATP-induced synthesis of interleukin-6 in osteoblasts: amplification of p38 MAP kinase.
Cell Biochem. Funct. 2021;39:88-97.

2. Kuroyanagi G, Sakai G, Otsuka T, Yamamoto N, Fujita K, Kawabata T, Matsushima-Nishiwaki R, Kozawa O and Tokuda H.
HSP22 (HSPB8) positively regulates PGF2α-induced synthesis of interleukin-6 and vascular endothelial growth factor in osteoblasts.
J. Orth. Surg. Res. 2021;39:88-97.

3. Kim W, Tokuda H, Tanabe K, Yamaguchi S, Hioki T, Tachi J, Matsushima-Nishiwaki R, Kozawa O and Iida H.
Acetaminophen reduces osteoprotegerin synthesis by PGE2 and PGF2α in osteoblasts: attenuation of SAPK/JNK but not p38 MAPK and p44/p42 MAPK.
Biomed. Res. 2021;42:77-84.

4. Yamada N, Matsushima-Nishiwaki R, Kobayashi K, Tachi J and Kozawa O.
GLP-1 reduces the migration of hepatocellular carcinoma cells via suppression of the stress-activated protein kinase/c-Jun N-terminal kinase pathway.
Arch. Biochem. Biophys. 2021;703:108851.

5. Hioki T, Tokuda H, Kuroyanagi G, Kim W, Tachi J, Matsushima-Nishiwaki R, Iida H and Kozawa O.
Olive polyphenols attenuate TNF-α-stimulated M-CSF and IL-6 synthesis in osteoblasts: Suppression of Akt and p44/p42 MAPK signaling pathways.
Biomed. Pharmacother. 2021;141:111816.

6. Tachi J, Onuma T, Yamaguchi S, Kim W, Hioki T, Matsushima-Nishiwaki R, Tanabe K, Tokuda H, Kozawa O and Iida H.
Duloxetine suppresses BMP-4-induced release of osteoprotegerin via inhibition of the SMAD signaling pathway in osteoblasts.
Biochem. Cell Biol. 2021;99:578-586.

7. Hioki T, Tokuda H, Tanabe K, Kim W, Tachi J, Yamaguchi S, Matsushima-Nishiwaki R, Kozawa O and Iida H.
Amplification by tramadol of PGD2-induced osteoprotegerin synthesis in osteoblasts:involvement of μ-opioid receptor and 5-HT transporter.
Prostaglandins Leukot. Essent. Fatty Acids2021;172:102323.

8. Yamada N, Matsushima-Nishiwaki R, Kobayashi K, Takahata S, Toyoda H, Kumada T and Kozawa O.
Cellular functions of small heat shock proteins (HSPB) in hepatocellular carcinoma.
Curr. Mol. Med. 2021;21:872-887.