Department of Pharmacology, Gifu University Graduate School of Medicine




研究業績リスト
Original Article
  [2016]
1. Tanabe K, Kozawa O and Iida H. cAMP/PKA enhances interleukin-1β-induced interleukin-6 synthesis through STAT3 in glial cells.
Cell Signal.2016;28:19-24.
2. Kuroyanagi G, Otsuka T, Yamamoto N, Kainuma S, Ohguchi R, Fujita K, Matsushima-Nishiwaki R, Kozawa O and Tokuda H. Mimosine suppresses the PGF-induced synthesis of osteoprotegerin but not interleukin-6 in osteoblasts.
Int J Mol Med.2016;37:533-541.
3. Kainuma S, Otsuka T, Kuroyanagi G, Yamamoto N, Matsushima-Nishiwaki R, Kozawa O and Tokuda H.Possible involvement of AMP-activated protein kinase in PGE1-induced synthesis of osteoprotegerin in osteoblasts.
Exp Ther Med.2016;11:2042-2048.
4. Tsujimoto M, Tokuda H, Kuroyanagi G, Yamamoto N, Kainuma S, Matsushima- Nishiwaki R, Onuma T, Iida Y, Kojima A, Sawada S, Doi T, Enomoto Y, Tanabe K, Akamatsu S, Iida H, Ogura S, Otsuka T, Kozawa O and Iwama T. AICAR reduces the collagen-stimulated secretion of PDGF-AB and release of soluble CD40 ligand from human platelets: suppression of HSP27 phosphorylation via p44/p42 MAP kinase.
Exp Ther Med.2016;12:1107-1112.
5. Kainuma S, Otsuka T, Kuroyanagi G, Yamamoto N, Matsushima-Nishiwaki R, Kozawa O and Tokuda H. Regulation by AMP-activated protein kinase of PGE2-induced osteoprotegerin synthesis in osteoblasts.
Mol Med Rep.2016;13:3363-3369.
6. Tsujimoto M, Kuroyanagi G, Matsushima-Nishiwaki R, Kito Y, Enomoto Y, Iida H, Ogura S, Otsuka T, Tokuda H, Kozawa O and Iwama T. Factor Xa inhibitor suppresses the release of phosphorylated HSP27 from collagen-stimulated human platelets: inhibition of HSP27 phosphorylation via p44/p42 MAP kinase.
PLoS One.2016;11:e0149077.
7. Okuno M, Yasuda I, Adachi S, Nakashima M, Kawaguchi J, Doi S, Iwashita T, Hirose Y, Kozawa O, Yoshimi N, Shimizu M and Moriwaki H. The significance of phosphorylated heat shock protein 27 on the prognosis of pancreatic cancer.
Oncotarget.2016;7:14291-14299.
8. Matsushima-Nishiwaki R, Toyoda H, Nagasawa T, Yasuda E, Chiba N, Okuda S, Maeda A, Kaneoka Y, Kumada T and Kozawa O. Phosphorylated heat shock protein 20 (HSPB6) regulates transforming growth factor-α-induced migration and invasion of hepatocellular carcinoma cells.
PLoS One.2016;11:e0151907.
9. Tokuda H, Kuroyanagi G, Tsujimoto M, Matsushima-Nishiwaki R, Akamatsu S, Enomoto Y, Iida H, Otsuka T, Ogura S, Iwama T, Kojima K and Kozawa O. Thrombin receptor-activating protein (TRAP)-activated Akt is involved in the release of phosphorylated-HSP27 (HSPB1) from platelets in DM patients.
Int J Mol Sci.2016;17:737.
10. Horibe Y, Adachi S, Yasuda I, Yamauchi T, Kawaguchi J, Kozawa O, Shimizu M and Moriwaki H. Anticancer effect of arsenite on cell migration, cell cycle and apoptosis in human pancreatic cancer cells.
Oncol Lett.2016;12:177-182.
11. Yamamoto N, Tokuda H, Kuroyanagi G, Kainuma S, Matsushima-Nishiwaki R, Fujita K, Kozawa O and Otsuka T. Heat shock protein 22 (HSPB8) limits TGF-β- stimulated migration of osteoblasts.
Mol Cell Endocrinol.2016;436:1-9.
12.  Kainuma S, Tokuda H, Fujita K, Kawabata T, Sakai G, Matsushima-Nishiwaki R, Harada A, Kozawa O and Otsuka T. Attenuation by incretins of thyroid hormone- stimulated osteocalcin synthesis in osteoblasts. .
Biomed Rep. 2016;5:771-775.
   
  Review Article
1. Okuno M, Adachi S, Kozawa O, Shimizu M and Yasuda I. The clinical significance of phosphorylated heat shock protein 27 (HSPB1) in pancreatic cancer.
Int J Mol Sci.2016;17:137.



Department of Pharmacology, Gifu University Graduate School of Medicine