Department of Pharmacology, Gifu University Graduate School of Medicine




研究業績リスト
Original Article
  [2015]
1. Tsujimoto M, Doi T, Kuroyanagi G, Yamamoto N, Matsushima-Nishiwaki R, Iida Y, Enomoto Y, Iida H, Ogura S, Otsuka T, Tokuda H, Kozawa O and Iwama T. αB-crystallin reduces ristocetin-induced soluble CD40 ligand release in human platelets: suppression of thromboxane A2 generation.
Mol. Med. Rep. 2015;12:357-362.
2. Kuroyanagi G, Tokuda H, Yamamoto N, Matsushima-Nishiwaki R, Mizutani J, Kozawa O and Otsuka T. Resveratrol amplifies BMP-4-stimulated osteoprotegerin synthesis via p38 MAP kinase in osteoblasts.
Mol. Med. Rep. 2015;12:3849-3854.
3. Nagasawa T, Matsushima-Nishiwaki R, Yasuda E, Matsuura J, Toyoda H, Kaneoka Y, Kumada T and Kozawa O. Heat shock protein 20 (HSPB6) regulates TNF-α-induced intracellular signaling pathway in human hepatocellular carcinoma cells.
Arch. Biochem. Biophys. 2015;565:1-8.
4. Iida Y, Doi T, Tokuda H, Matsushima-Nishiwaki R, Tsujimoto M, Kuroyanagi G, Yamamoto N, Enomoto Y, Tanabe K, Otsuka T, Iwama T, Ogura S, Kozawa O and Iida H. Rho-kinase regulates human platelet activation induced by thromboxane A2 independently of p38 MAP kinase.
Prostaglandins Leukot. Essent. Fatty Acids. 2015;94:73-81.
5. Yamamoto N, Otsuka T, Kuroyanagi G, Kondo A, Kainuma S, Nakakami A, Matsushima-Nishiwaki R, Kozawa O and Tokuda H. Resveratrol reduces prostaglandin E1-stimulated osteoprotegerin synthesis in osteoblasts: suppression of stress-activated protein kinase/c-Jun N-terminal kinase.
Prostag. Oth. Lipid M. 2015;116-117:57-63.
6. Yamamoto N, Otsuka T, Kondo A, Matsushima-Nishiwaki R, Kuroyanagi G, Kozawa O and Tokuda H. Rac limits TGF-β-induced VEGF synthesis in osteoblasts.
Mol. Cell. Endocrinol. 2015;405:35-41.
7. Suzuki M, Matsushima-Nishiwaki R, Kuroyanagi G, Suzuki N, Takamatsu R, Furui T, Yoshimi N, Kozawa O and Morishige KI. Regulation by heat shock protein 22 (HSPB8) of transforming growth factor-α-induced ovary cancer cell migration.
Arch. Biochem. Biophys. 2015;571:40-49.
8. Kuroyanagi G, Tokuda H, Yamamoto N, Matsushima-Nishiwaki R, Kozawa O and Otsuka T. Unphosphorylated HSP27 (HSPB1) regulates the translation initiation process via a direct association with eIF4E in osteoblasts.
Int. J. Mol. Med. 2015;36:881-889.
9. Kuroyanagi G, Otsuka T, Yamamoto N, Matsushima-Nishiwaki R, Kozawa O, and Tokuda H. Resveratrol suppresses TGF-β-induced VEGF synthesis in osteoblasts: inhibition of the p44/p42 MAP kinase and SAPK/JNK pathways.
Exp. Ther. Med. 2015;9:2303-2310.
10. Tokuda H, Kuroyanagi G, Tsujimoto M, Enomoto Y, Matsushima-Nishiwaki R, Onuma T, Kojima A, Doi T, Tanabe K, Akamatsu S, Iida H, Ogura S, Otsuka T, Iwama T, Tanikawa T, Ishikawa K, Kojima K and Kozawa O. Release of phosphorylated HSP27 (HSPB1) from platelets is accompanied with the acceleration of aggregation in diabetic patients.
PLoS One 2015;10:e0128977.
11. Kainuma S, Tokuda H, Kuroyanagi G, Yamamoto N, Ohguchi R, Fujita K, Matsushima-Nishiwaki R, Kozawa O and Otsuka T. PGD2 stimulates osteoprotegerin synthesis via AMP-activated protein kinase in osteoblasts:regulation of ERK and SAPK/JNK.
Prostaglandins Leukot. Essent. Fatty Acids. 2015;101:23-29.
12.  Yamamoto N, Tokuda H, Kuroyanagi G, Kainuma S, Ohguchi R, Fujita K, Matsushima-Nishiwaki R, Kozawa O and Otsuka T. Amplification by (-)-epigallocatechin gallate and chlorogenic acid of TNF-α-stimulated interleukin-6 synthesis in osteoblasts.
Int. J. Mol. Med. 2015;36:1707-1712.



Department of Pharmacology, Gifu University Graduate School of Medicine