Department of Pharmacology, Gifu University Graduate School of Medicine




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@ [2012]
1. Kato K, Otsuka T, Kondo A, Matsushima-Nishiwaki R, Natsume H, Kozawa O and Tokuda H. AMP-activated protein kinase regulates PDGF-BB-stimulated interleukin-6 synthesis in osteoblasts: involvement of mitogen-activated protein kinases.
Life Sci. 2012;90:71-76.
2. Kawaguchi J, Adachi S, Yasuda I, Yamauchi T, Yoshioka T, Itani M, Kozawa O and Moriwaki H. UVC irradiation suppresses platelet-derived growth factor-BB-induced migration in human pancreatic cancer cells.
Oncol. Rep. 2012;27:935-939.

3. Mizutani J, Tokuda H, Matsushima-Nishiwaki R, Kato K, Kondo A, Natsume H, Kozawa O and Otsuka T. Involvement of AMP-activated protein kinase in TGF--stimulated VEGF synthesis in osteoblasts.
Int. J. Mol. Med. 2012;29:550-556.
4. Kondo A, Otsuka T, Natsume H, Matsushima-Nishiwaki R, Kato K, Kozawa O and Tokuda H. Wnt3a up-regulates prostaglandin F2-stimulated VEGF synthesis in osteoblasts.
Mol. Med. Rep. 2012;6:421-425.
5. Kato K, Tokuda H, Matsushima-Nishiwaki R, Natsume H, Kondo A, Ito Y, Kozawa O and Otsuka T. AMPK limits IL-1-stimulated IL-6 synthesis in osteoblasts: involvement of IkB/NF-kB pathway.
Cell. Signal. 2012;24:1706-1712.

6. Kawaguchi J, Adachi S, Yasuda I, Yamauchi T, Nakashima M, Ohno T, Shimizu M, Yoshioka T, Itani M, Kozawa O and Moriwaki H. Cisplatin and ultra-violet-C synergistically down-regulate receptor tyrosine kinases in human colorectal cancer cells.
Mol. Cancer. 2012;11:45.

7. Tanabe K, Matsushima-Nishiwaki R, Iida M, Kozawa O and Iida H. Involvement of phosphatidylinositol 3-kinase/Akt on basic fibroblast growth factor-induced glial cell line-derived neurotrophic factor release from rat glioma cells.
Brain Res. 2012;1463:21-29.
8. Tokuda H, Kato K, Natsume H, Kondo A, Kuroyanagi G, Matsushima-Nishiwaki R, Ito Y, Otsuka T and Kozawa O. Involvement of AMP-activated protein kinase in thrombin-stimulated interleukin-6 synthesis in osteoblasts.
J. Mol. Endocrinol. 2012;49:47-55.

9. Doi T, Tokuda H, Matsushima-Nishiwaki R, Cuong NT, Kageyama Y, Iida Y, Kondo A, Akamatsu S, Otsuka T, Iida H, Kozawa O and Ogura S. Effect of antithrombin III on glycoprotein Ib/IX/V activation in human platelets: suppression of thromboxane A2 generation.
Prostaglandins Leukot. Essent. Fatty Acids. 2012;87:57-62.
10. Tokuda H, Kato K, Kasahara S, Matsushima-Nishiwaki R, Mizuno T, Sakakibara S and Kozawa O. Significant correlation between the acceleration of platelet aggregation and phosphorylation of HSP27 at Ser-78 in diabetic patients.
Int. J. Mol. Med. 2012;30:1387-1395.

11. Kondo A, Otsuka T, Kato K, Natsume H, Kuroyanagi G, Mizutani J, Ito Y, Matsushima-Nishiwaki R, Kozawa O and Tokuda H. AMP-activated protein kinase inhibitor decreases prostaglandin F2-stimulated interleukin-6 synthesis through p38 MAP kinase in osteoblasts.
Int. J. Mol. Med. 2012;30:1487-1492.



Department of Pharmacology, Gifu University Graduate School of Medicine