Department of Pharmacology, Gifu University Graduate School of Medicine


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@[2006]

1. Takai S, Tokuda H, Matsushima-Nishiwaki R, Hanai Y, Kato K and Kozawa O. Phosphatidylinositol 3-kinase/Akt plays a role in sphingosine 1-phosphate-stimulated HSP27 induction in osteoblasts.@

J. Cell. Biochem. 2006;98:1249-1256.

2. Hanai Y, Tokuda H, Takai S, Harada A, Ohta T and Kozawa O. Minodronate suppresses prostaglandin F2a-induced vascular endothelial growth factor synthesis in osteoblasts.

Horm. Metab. Res. 2006;38:152-158.

3. Tanabe K, Tokuda H, Takai S, Matsushima-Nishiwaki R, Hanai Y, Hirade K, Katagiri Y, Dohi S and Kozawa O. Modulation by the steroid/thyroid hormone superfamily of TGF-b-stimulated VEGF release from vascular smooth muscle cells.

J. Cell. Biochem. 2006;99:187-195.

4. Hanai Y, Tokuda H, Ishisaki A, Matsushima-Nishiwaki R, Nakamura N, Yoshida M, Takai S, Ohta T and Kozawa O. Involvement of p44/p42 MAP kinase in insulin-like growth factor-I-induced alkaline phosphatase activity in osteoblast-like MC3T3-E1 cells.

Mol. Cell. Endocrinol. 2006;251:42-48.

5. Hara A, Niwa M, Kumada M, Aoki H, Kunisada T, Oyama T, Yamamoto T, Kozawa O and Mori H. Intraocular injection of folate antagonist, methotrexate induces neuronal differentiation of embryonic stem cells transplanted in the adult mouse retina.

Brain Res. 2006;1058:33-42.

6. Nakajima K, Suga H, Matsuno H, Ishisaki A, Hirade K and Kozawa O. Differential roles of MAP kinases in atorvastatin-induced VEGF release in cardiac myocytes.

Life Sci. 2006;79:1214-1220.

7. Hanai Y, Tokuda H, Ohta T, Matsushima-Nishiwaki R, Takai S and Kozawa O. Phosphatidylinositol 3-kinase/Akt auto-regulates PDGF-BB-stimulated interleukin-6 synthesis in osteoblasts.

J. Cell. Biochem. 2006;99:1564-1571.

8. Takai S, Tokuda H, Yoshida M, Yasuda E, Matsushima-Nishiwaki R, Harada A, Kato K and Kozawa O. Prostaglandin D2 induces the phosphorylation of HSP27 in osteoblasts: function of the MAP kinase superfamily.

Prostaglandins Leukot. Essent. Fatty Acids. 2006;75:61-67.

9. Hara A, Niwa M, Aoki H, Kumada M, Kunisada T, Oyama T, Yamamoto T, Kozawa O and Mori H. A new model of retinal photoreceptor cell degeneration by a chemical hypoxia-mimicking agent, cobalt chloride.

Brain Res. 2006;1109:192-200.

10. Takai S, Tokuda H, Hanai Y and Kozawa O. Phosphatidylinositol 3-kinase/Akt plays a part in tumor-necrosis factor-a-induced interleukin-6 synthesis in osteoblasts.

Horm. Metab. Res. 2006;38:563-569.

11. Niwa M, Hotta K, Hara A, Hirade K, Ito H, Kato K and Kozawa O. TNF-a decreases HSP 27 in human blood mononuclear cells: involvement of protein kinase C.

Life Sci. 2006;80:181-186.

12. Hanai Y, Tokuda H, Yasuda E, Noda T, Ohta T, Takai S and Kozawa O. Up-regulation by zinc of FGF-2-induced VEGF release through enhancing p44/p42 MAP kinase activation in osteoblasts.

Life Sci. 2006;80:230-234.


Department of Pharmacology, Gifu University Graduate School of Medicine