Department of Pharmacology, Gifu University Graduate School of Medicine


研究業績リスト

 [2003]
1. Takenaka M, Hirade K, Tanabe K, Akamatsu S, Dohi S, Matsuno H and Kozawa O:
  Simvastatin stimulates VEGF release via p44/p42 MAP kinase in vascular
  smooth muscle cells.
  Biochem. Biophys Res. Commun. 301;198-203, 2003  
2. Tanabe K, Dohi S, Matsuno H, Hirade K and Kozawa O: Midazolam stimulates
  vascular endothelial growth factor release in aortic smooth muscle cells
  : role of the mitogen-activated protein kinase superfamily.
  Anesthesiology 98;1147-1154, 2003  
3. Tokuda H, Kato K, Oiso Y and Kozawa O: Contrasting effects of triiodothyronine
  on heat shock protein 27 induction and vascular endothelial growth factor
  synthesis stimulated TGF- in osteoblasts.
  Mol. Cell. Endocrinol. 201;33-38, 2003  
4. Tokuda H, Hirade K, Wang X, Oiso Y and Kozawa O: Involvement of SAPK/JNK
  in basic fibroblast growth factor-induced VEGF release in osteoblasts.
  J. Endocrinol. 177;101-107, 2003  
5. Tokuda H, Hatakeyama D, Shibata T, Akamatsu S, Oiso Y and Kozawa O: p38
  MAP kinase regulates BMP-4-stimulated VEGF synthesis via p70 S6 kinase in
  osteoblasts.
  Am. J. Physiol. Endocrinology and Metabolism Physiology 284;E1202-1209, 2003  
6. Niwa M, Hotta K, Kanamori Y, Hatakeyama D, Hirade K, Katayama M, Hara A,
  Mori H, Ito H, Kato K, Matsuno H, Uematsu T and Kozawa O: Involvement of p38
  mitogen-activated protein kinase in heat shock protein 27 induction in human
  neutrophils.
  Eur. J. Pharmacol. 466;245-253, 2003
7. Tokuda H, Harada A, Hirade K, Matsuno H, Ito H, Kato K, Oiso Y and Kozawa O:
  Incadronate amplifies prostaglandin F2 -induced vascular endothelial growth
  factor in osteoblasts: enhancement of MAP kinase activity.
  J. Biol. Chem. 278;18930-18937, 2003
8. Wang X, Tokuda H, Hatakeyama D, Hirade K, Niwa M, Ito H, Kato K and Kozawa O:
  Mechanism of simvastatin on induction of heat shock protein in osteoblasts.
  Arch. Biochem. Biophys. 415;6-13, 2003
9. Tokuda H, Hatakeyama D, Akamatsu S, Tanabe K, Yoshida M, Shibata T and
  Kozawa O: Involvement of MAP kinases in TGF- -stimulated vascular endothelial
  growth factor synthesis in osteoblasts.
  Arch. Biochem. Biophys. 415;117-125, 2003
10. Matsuno H, Okada K, Ueshima S, Matsuo O and Kozawa O: 2-antiplasmin plays
  a significant role in acute pulmonary embolism.
  J. Thromb. Haemost. 1:1734-1739, 2003
11. Tokuda H, Niwa M, Ito H, Oiso Y, Kato K and Kozawa O: Involvement of
  stress-activated protein kinase (SAPK)/c-Jun N-terminal kinase (JNK) in
  endothelin-1-induced heat shock protein 27 in osteoblasts.
  Eur. J. Endocrinol. 149;239-245, 2003
12. Matsuno H, Ishisaki A, Nakajima K, Okada K, Ueshima S, Matsuo O and Kozawa
  O: Lack of 2-antiplasmin promotes reendothelialization via over-release of VEGF
  after vascular injury in mice.
  Blood 102;3621-3628, 2003
13. Matsuno H, Ishisaki A, Nakajima K, Kato K and Kozawa O: A peptide isolated
  from B-crystallin is a novel and potent inhibitor of platelet aggregation via dual
  prevension of PAR-1 and GPIb/V/IX.
  J. Thromb. Haemost. 1:2636-2642, 2003



Department of Pharmacology, Gifu University Graduate School of Medicine