Shun Yamaguchi transferred to Gifu University from Kobe University in 2011.
E-mail address was changed from shunyama@med.kobe-u.ac.jp to shunyama@gifu-u.ac.jp.

Key words: Arc, Arc-dVenus, transgenic mice, visualization, promoter, luciferase, mPer1, circadian



Publications:                              

Susaki EA, Tainaka K, Perrin D, Kishino F, Tawara T, Watanabe TM, Yokoyama C, Onoe H, Eguchi M, Yamaguchi S, Abe T, Kiyonari H, Shimizu Y, Miyawaki A, Yokota H, Ueda HR: Whole-brain imaging with single-cell resolution using chemical cocktails and computational analysis. Cell 157 (3), 726-739, 2014 (electronic publication, 17 April 2014, doi: 10.1016/j.cell.2014.03.042)

Mizunuma M, Norimoto H, Tao K, Egawa T, Hanaoka K, Sakaguchi T, Hioki H, Kaneko T, Yamaguchi S, Nagano T, Matsuki N, Ikegaya Y: Unbalanced excitability underlies offline reactivation of behaviorally activated neurons. Nat Neurosci 17 (4), 503-505, 2014 (electronic publication, 16 March 2014, doi: 10.1038/nn.3674)

Ohira K, Kobayashi K, Toyama K, Nakamura HK, Shoji H, Takao K, Takeuchi R, Yamaguchi S, Kataoka M, Otsuka S, Takahashi M, Miyakawa T: Synaptosomal-associated protein 25 mutation induces immaturity of the dentate granule cells of adult mice. Mol Brain 6 (12), 1-17, 2013 (electronic publication, 12 March 2013, doi: 10.1186/1756-6606-6-12)

Takao K, Kobayashi K, Hagihara H, Ohira K, Shoji H, Hattori S, Koshimizu H, Umemori J, Toyama K, Nakamura HK, Kuroiwa M, Maeda J, Atsuzawa K, Esaki K, Yamaguchi S, Furuya S, Takagi T, Walton NM, Hayashi N, Suzuki H, Higuchi M, Usuda N, Suhara T, Nishi A, Matsumoto M, Ishii S, Miyakawa T: Deficiency of Schnurri-2, an MHC enhancer binding protein, induces mild chronic inflammation in the brain and confers molecular, neuronal, and behavioral phenotypes related to schizophrenia. Neuropsychopharmacology 38 (8), 1409-1425, 2013 (electronic publication, 6 February 2013, doi: 10.1038/npp.2013.38)

Rudinskiy N, Hawkes JM, Betensky RA, Eguchi M, Yamaguchi S, Spires-Jones TL, Hyman BT: Orchestrated experience-driven Arc responses are disrupted in a mouse model of Alzheimer's disease.
Nat Neurosci 15 (10), 1422-1429, 2012 (electronic publication, 26 August 2012, doi: 10.1038/nn.3199)

Shinohara Y, Hosoya A, Ahmed H, Yamasaki N, Hattori S, Eguchi M, Yamaguchi S, Miyakawa T, Hirase H, Shigemoto R: Right-hemispheric dominance of spatial memory in split-brain mice. Hippocampus 22 (2), 117-121, 2012 (electronic publication, 10 November 2010, doi: 10.1002/hipo.20886)

Matsuo N, Yamasaki N, Ohira K, Takao K, Toyama K, Eguchi M, Yamaguchi S, Miyakawa T: Neural activity changes underlying the working memory deficit in alpha-CaMKII heterozygous knockout mice. Front Behav Neurosci 3 (20), 1-10, 2009 (electronic publication, 2 September 2009, doi: 10.3389/neuro.08.020.2009)

Eguchi M, Yamaguchi S: In vivo and in vitro visualization of gene expression dynamics over extensive areas of the brain. Neuroimage 44 (4), 1274-1283, 2009 (electronic publication, 12 November 2008, doi: 10.1016/j.neuroimage.2008.10.046)

Eguchi M, Yamaguchi S: Double transfection into primary dissociated neurons. J Biosci Bioeng 103 (5), 497-499, 2007

Iijima M, Yamaguchi S, van der Horst GT, Bonnefont X, Okamura H, Shibata S: Altered food-anticipatory activity rhythm in Cryptochrome-deficient mice. Neurosci Res 52 (2), 166-73, 2005

Yamaguchi S, Isejima H, Matsuo T, Okura R, Yagita K, Kobayashi M, Okamura H: Synchronization of cellular clocks in the suprachiasmatic nucleus. Science 302, 1408-1412, 2003

Matsuo T, Yamaguchi S (the first two authors are equal contributors to this work), Mitsui S, Emi A, Shimoda F, Okamura H: Control mechanism of the circadian clock for timing of cell division in vivo. Science 302, 255-259, 2003

Nomura K, Takeuchi Y, Yamaguchi S, Okamura H, Fukunaga K: Involvement of calcium/calmodulin-dependent protein kinase II in the induction of mPer1. J Neurosci Res 72 (3), 384-392, 2003

Sujino M, Masumoto K, Yamaguchi S, van der Horst GT, Okamura H, Inouye ST: Suprachiasmatic nucleus grafts restore circadian behavioral rhythms of genetically arrhythmic mice. Curr Biol 13 (8), 664-668, 2003

Terazono H, Mutoh T, Yamaguchi S, Kobayashi M, Akiyama M, Udo R, Ohdo S, Okamura H, Shibata S: Adrenergic regulation of clock gene expression in the mouse liver. Proc Natl Acad Sci U S A 100 (11), 6795-6800, 2003

Okamura H, Yamaguchi S, Yagita K: Molecular machinery of the circadian clock in mammals. Cell Tissue Res 309, 47-56, 2002

Onishi H, Yamaguchi S, Yagita K, Ishida Y, Dong X, Kimura H, Jing Z, Ohara H, Okamura H: Rev-erb alpha gene expression in the mouse brain with spatial emphasis on its circadian profiles in the suprachiasmatic nucleus. J Neurosci Res 68, 551-557, 2002

Ishida Y, Yokoyama C, Inatomi T, Yagita K, Dong X, Yan L, Yamaguchi S, Nagatsu I, Komori T, Kitahama K, Okamura H: Circadian rhythm of aromatic L-amino acid decarboxylase in the rat suprachiasmatic nucleus: gene expression and decarboxylating activity in clock oscillating cells. Genes Cells 7 (5), 447-459, 2002

Sumi Y, Yagita K, Yamaguchi S, Ishida Y, Kuroda Y, Okamura H: Rhythmic expression of ROR beta mRNA in the mice suprachiasmatic nucleus. Neurosci Lett 320 (1-2), 13-16, 2002

Taguchi K, Okura R, Yagita K, Ishida Y, Onishi H, Shigeyoshi Y, Yamaguchi S, Nishimura M, Masubuchi S, Okamura H: Different circadian expression profiles of clock genes in the mouse suprachiasmatic nucleus. Biomed Res 22 (3), 125-131, 2001

Asai M, Yamaguchi S (the first two authors are equal contributors to this work), Isejima H, Jonouchi M, Moriya T, Shibata S, Kobayashi M, Okamura H: Visualization of mPer1 transcription in vitro: NMDA induces a rapid phase shift of mPer1 gene in cultured SCN. Curr Biol 11 (19), 1524-1527, 2001

Ishida Y, Yagita K, Fukuyama T, Nishimura M, Nagano M, Shigeyoshi Y, Yamaguchi S, Komori T, Okamura H: Constitutive expression and delayed light response of casein kinase I epsilon and I delta mRNAs in the mouse suprachiasmatic nucleus. J Neurosci Res 64 (6), 612-616, 2001

Nishiyama K, Yagita K, Yamaguchi S, Kitamura S, Matsuo T, Uno T, Tanaka M, Hisa Y, Ibata Y, Okamura H: Tyrosine hydroxylase and NADPH-diaphorase in the rat nodose ganglion: colocalization and central projection. Acta Histochem Cytochem 34 (2), 135-141, 2001

Mitsui S, Yamaguchi S (the first two authors are equal contributors to this work), Matsuo T, Ishida Y, Okamura H: Antagonistic role of E4BP4 and PAR proteins in the circadian oscillatory mechanism. Genes Dev 15, 995-1006, 2001

Nakamura T, Shigeyoshi Y, Maebayashi Y, Yamaguchi S, Yagita K, Okamura H: Different developmental profiles of the expression of preprosomatostatin and preprotachykinin-A mRNAs in rat SCN neurons. Brain Res Dev Brain Res 127 (1), 81-86, 2001

Yamamoto S, Shigeyoshi Y, Ishida Y, Fukuyama T, Yamaguchi S, Yagita K, Moriya T, Shibata S, Takashima N, Okamura H: Expression of the Per1 gene in the hamster: Brain atlas and circadian characteristics in the suprachiasmatic nucleus. J Comp Neurol 430, 518-532, 2001

Yamaguchi S, Kobayashi M, Mitsui S, Ishida Y, van der Horst GT, Suzuki M, Shibata S, Okamura H: View of a mouse clock gene ticking. Nature 409, 684-684, 2001

Sugano T, Yagita K, Ibata Y, Nagatsu I, Tanaka M, Yamaguchi S, Okamura H: Morphological survey of reserpine-induced tyrosine hydroxylase in brainstem dopaminergic, noradrenergic and adrenergic neurons with special reference to their projection fibers. Biomed Res 21 (5), 269-282, 2000

Miyake S, Sumi Y, Yan L, Takekida S, Fukuyama T, Ishida Y, Yamaguchi S, Yagita K, Okamura H: Phase-dependent responses of Per1 and Per2 genes to a light-stimulus in the suprachiasmatic nucleus of the rat. Neurosci Lett 294 (1), 41-44, 2000

Yamaguchi S, Mitsui S, Miyake S, Yan L, Onishi H, Yagita K, Suzuki M, Shibata S, Kobayashi M, Okamura H: The 5' upstream region of mPer1 gene contains two promoters and is responsible for circadian oscillation. Curr Biol 10 (14), 873-876, 2000

Yamaguchi S, Mitsui S, Yan L, Yagita K, Miyake S, Okamura H: Role of DBP in the circadian oscillatory mechanism. Mol Cell Biol 20 (13), 4773-4781, 2000

Yagita K, Yamaguchi S, Tamanini F, van der Horst GT, Hoeijmakers JH, Yasui A, Loros JJ, Dunlap JC, Okamura H: Dimerization and nuclear entry of mPER proteins in mammalian cells. Genes Dev 14 (11), 1353-1363, 2000

Okamura H, Miyake S, Sumi Y, Yamaguchi S, Yasui A, Muijtjens M, Hoeijmakers JH, van der Horst GT: Photic induction of mPer1 and mPer2 in cry-deficient mice lacking a biological clock. Science 286 (5449), 2531-2534, 1999

Nakanishi S, Nakajima Y, Masu M, Ueda Y, Nakahara K, Watanabe D, Yamaguchi S, Kawabata S, Okada M: Glutamate receptors: brain function and signal transduction. Brain Res Brain Res Rev 26, 230-235, 1998

Yamaguchi S, Nakanishi S: Regional expression and regulation of alternative forms of mRNAs derived from two distinct transcription initiation sites of the rat mGluR5 gene. J Neurochem 71 (1), 60-68, 1998