生 化 学 講 座
 
著書 (和文)
野澤義則:生体膜の異常に基づく疾患, バイオメンブランシステム−生体膜と生命現象. 水島昭二, 宇井理生編, 東京,講談社サイエンティフィク, 1993. 172-178
 
中島 茂, 野澤義則:生体膜リン脂質代謝とその生理的意義, 最新生体膜システム. 水島昭二, 宇井理生編, 東京,講談社サイエンティフィク, 1993. 89-96
 
永田浩一, 野澤義則:GTP 結合蛋白質と血小板, Annual Review 血液1993.高久史麿, 宮崎澄雄, 斉藤英彦, 溝口秀昭編, 東京, 中外医学社, 1993. 175-183
 
野澤義則: メディエーターによる酵素活性の調節, 酵素実験法U. 大野素徳, 崎山文夫, 高橋健治編, 東京,廣川書店, 1993. 595-612
 
野澤義則, 中島 茂:Phospholipase C 系 − IP 3 と DG, 生体における情報伝達. 田中千賀子, 西塚泰美編, 東京,南江堂, 1993. 188-195

相原英孝, 大森正英, 尾庭きよ子, 竹中晃子, 田村 明, 長村洋一, 野澤義則:イラスト生化学入門−栄養素の旅−. 東京,東京教学社, 1993. 175p
 
加納宏行, 野澤義則:カルシウムのシグナル伝達機構, Bioscience Series. 小島 至編, 東京, 中外医学社, 1993. 26-39
 
永田浩一, 中島 茂, 野澤義則:G タンパク質とホスホリパーゼ, レセプター −基礎と臨床−. 井村裕夫, 岡 哲雄, 芳賀達也, 岸本英爾編, 東京,朝倉書店, 1993. 56-66
 
野澤義則, 金保安則:ホスホリパーゼ系, 膜学実験シリーズ (生体膜編). 野澤義則, 神野耕太郎, 井上圭三, 大木和夫編, 東京, 共立出版, 1994. 49-54
 
中島 茂:血小板膜, 膜学実験シリーズ (生体膜編). 野澤義則, 神野耕太郎, 井上圭三, 大木和夫編, 東京, 共立出版, 1994. 82-86
 
永田浩一:クロマトグラフィーによる蛋白質精製, 膜学実験シリーズ (生体膜編). 野澤義則, 神野耕太郎, 井上圭三, 大木和夫編, 東京, 共立出版, 1994. 125-129
 
野澤義則:原生動物細胞オルガネラ, 膜学実験シリーズ (生体膜編). 野澤義則, 神野耕太郎, 井上圭三, 大木和夫編, 東京, 共立出版, 1994. 108-111
 
野澤義則:スフィンゴシン, KEY WORD 1994-'95 炎症・免疫系. 柏崎禎夫, 室田誠逸編, 東京, 先端医学社, 1994. 154-155
 
中島 茂, 野澤義則:セラミド, KEY WORD 1994-'95 炎症・免疫系. 柏崎禎夫, 室田誠逸編, 東京, 先端医学社, 1994. 162-163
 
加納宏行, 野澤義則:ホスホリパーゼ D, KEY WORD 1994-'95 炎症・免疫系. 柏崎禎夫, 室田誠逸編, 東京,先端医学社, 1994. 220-221
 
中島 茂, 野澤義則:血小板凝集の生化学, 血液病学 第 2 版. 三輪史朗, 青木延雄, 柴田 昭編, 東京, 文光堂, 1994. 309-317
 
野澤義則:脂質からみた生体膜, 生体膜−新しい膜学への道. 宇井理生, 香川靖雄, 春日雅人, 野澤義則編, 東京,講談社サイエンティフィク, 1995. 1-58
 
香川靖雄, 野澤義則:図説医化学, 第3 版 . 東京,南山堂, 1995. 506p
 
坂野喜子, 中島 茂, 野澤義則:第 4 章 細胞シグナル物質, ホスホリパーゼ A 2, C, D, [バイオマニュアル UP シリーズ] シグナル伝達実験法. 宇井理生編, 東京, 羊土社, 1996. 130-141
 
野澤義則, 熊田裕一:血管平滑筋のリン脂質シグナリング, 血管・血小板の生物学. 日高弘義, 大熊 稔, 蔵本 淳, 池田康夫, 島田和幸編, 東京, 金芳堂, 1996. 123-133
 
野澤義則:G 蛋白質と細胞内メッセンジャーの産生, 標準分子医化学. 藤田道也, 渋谷正史, 小島 至編, 東京,医学書院, 印刷中

中島 茂, 野澤義則:イノシトールリン脂質代謝産物受容体, レセプターー分子薬理学的アプローチ. 日高弘義編, 東京, 講談社サイエンティフィク, 印刷中
 
中島 茂, 野澤義則:細胞表層の分子構造と細胞間コミュニケーション, 分子生物学の展開, 第 3 巻 高等動物の分子生物学. 三浦謹一郎, 関口睦夫, 村松正實, 畑中正一, 山田康之編, 東京, 朝倉書店, 印刷中
 
岡野幸雄, 中島 茂, 野澤義則:IP 3 と DG, ニューロサイエンス講座 第 5 巻 二次メッセンジャーと産生酵素. 竹縄忠臣, 野村靖幸編, 東京,廣川書店, 印刷中
 
野澤義則:膜の構造とリン脂質の役割, 最新内科学大系, 内科総論, 第 2 巻 科学としての内科学. 井村裕夫編, 東京, 中山書店, 印刷中
 
足立尊仁, 野澤義則:リン脂質による情報伝達V. 肝における受容体と情報伝達 「肝臓病学」 (Basic Hepatology). 戸田剛太郎, 織田正也, 清澤研道, 坪内博仁, 中沼安二編, 東京,医学書院, 印刷中
 
野澤義則:情報伝達とリン脂質代謝, 生物薬科学実験講座 3 脂質. 井上圭三, 瀧 孝雄, 中川靖一編, 東京,廣川書店, 印刷中
 
加納宏行, 野澤義則:ホスファチジルイノシトールのリン酸化反応, 生物薬科学実験講座 3 脂質. 井上圭三, 瀧 孝雄, 中川靖一編, 東京,廣川書店, 印刷中
 
中島 茂, 野澤義則:ホスホリパーゼ A 2, 生物薬科学実験講座 5 生体膜の構造と機能. 石橋貞彦, 寺田 弘編, 東京,廣川書店, 印刷中
 
坂野喜子, 野澤義則:ホスホリパーゼ C, 生物薬科学実験講座 5 生体膜の構造と機能. 石橋貞彦, 寺田 弘編, 東京,廣川書店, 印刷中
 
金保安則, 野澤義則:ホスホリパーゼ D, 生物薬科学実験講座 5 生体膜の構造と機能. 石橋貞彦, 寺田 弘編, 東京,廣川書店, 印刷中
 
著書 (欧文)
Nozawa Y, Banno Y, Nagata K: Regulation of phosphoinositide-specific phospholipase C activity in human platelets, Advances in Experimental Medical and Biology, Vol.334, Mechanisms of Platelet Activation and Control, (ed Authi KS, Watson SP, Kakkar VV). Plenum Press, New York and London, 1993. 37-48
 
Umeki S, Nozawa Y: Lipid composition of membranes involved in membrane traffic in Tetrahymena, Advances in Cell and Molecular Biology of Membranes,Vol. 2B, Membrane Traffic in Protozoa, (ed Tartakoff A M, Plattner H). JAI Press Inc, Greenwich, 1993. 447-465

Nakashima S, Nozawa Y: Recoptor-mediated phspholipase D in secretory cells, Lipid Mediators in Health and Disease (LMHD), (ed Zor U). Freund Publishing House Ltd, London, 1994. 65-69

Hara A, Inazu A, Deyashiki Y, Nozawa Y: Substrate specificity and kinetic mechanism of Tetrahymena 20α-hydroxysteroid dehydrogenase, Advance in Experimental Medicine and Biology, Vol. 372, Enzymology and Molecular Biology of Carbonyl Metabolism, (ed Weiner H, Holmes RS, Wermuth B). Plenum Press, New York, 1995. 249-258
 
Nakashima S, Banno Y, Nozawa Y: Role of signal-transducing phospholipase A 2, C and D in platelet activation. Advances in Molecular and Cell Biology Series, Vol. 17, The Platelet, (ed Lapetina EG). JAI Press Inc, Greenwich, 1996. 253-274
 
Kitajima Y, Nozawa Y: Lipids and dimorphism of Candida albicans and Sporothrix schencki, Lipids of Pathogenic Fungi, (ed Prasad R, Ghannoum MA). CRC Press Inc, 1996. 215-230
 
Umeki S, Nozawa Y: Adenylate and guanylate cyclase in Tetrahymena. Progress in Molecular and Subcellular Biology, Vol. 17, Signaling Mechanisms in Protozoa and Invertebrates, (ed Csaba G, Muller N). Springer-Verlag, Berlin, 1996. 40-60
 
Nakashima S, Banno Y, Nozawa Y: Platelet phospholipase C, D, Handbook of Experimental Pharmacology, Vol. 126, Platelets and Their Factors, (ed Bruchhausen V, Walter U). Springer-Verlag, Heiderberg, in press
 
Higashida H, Hashii M, Yokoyama S, Taketo M, Hoshi N, Noda M, Zhong ZG, Shahidullah M, Minabe Y, Nakashima S, Nozawa Y: Bradykinin B 2 receptors and signal transduction analyzed in NG108-15 neuroblastoma x glioma hybrid cells, B 2 receptor-transformed CHO cells and ras-transformed NIH3T3 fibroblasts, Progress in Brain Reserch, (ed Kruger L). Elsevier Science Publisher B.V. in press
 
総説 (和文)
坂井隆之, 野沢義則:新しい情報変換酵素, ホスホリパーゼ D. 実験医学 (増刊 バイオシグナル実験法) 11, 80-84 (1993)
 
野沢義則:細胞膜シグナル変換の分子機構. 日皮会誌 103, 1525-1528 (1993)
 
岡野幸雄, 傳 涛, 野澤義則:画像解析法 (生物現象解析:Ca 2+ 濃度分布) 癌化線維芽細胞における Ca 2+ オシレーション. 日皮会誌 103, 1668-1669 (1993)
 
野澤義則:情報伝達におけるレシチン (PC) 分解とその意義−ホスホリパーゼ C, D を中心に. 生化学 65, 25-29 (1993)
 
野澤義則:膜リン脂質と細胞増殖シグナル. 特集:細胞増殖と疾患. MeBio 10, 52-58 (1993)
 
岡野幸雄, 野澤義則:c-MET/HGF レセプターとその細胞内情報伝達機構. 特集:HGF - 形態形成・組織再生・癌化. 実験医学 11, 34-40 (1993)
 
野澤義則:Candida albicans の二形性. 臨床と微生物 (増刊 微生物と感染症 21世紀への歩み) 120, 867-874 (1993)

野澤義則:レシチンと情報伝達. 特集:脂質研究−最近の話題. 医学のあゆみ 167, 835-838 (1993)
 
永田浩一, 野澤義則:シナプス分泌における GTP 結合蛋白質の機能. 特集:シナプス伝達−分泌機構研究の新展開. MeBio 10, 80-84 (1993)
 
野澤義則, 坂野喜子, 中島 茂:イノシトールリン脂質情報伝達研究の動向. 実験医学 (増刊 情報伝達研究の新しい展開) 11, 12-16 (1993)
 
永田浩一, 小池晃彦, 鈴木武志, 野澤義則:血小板活性化の情報伝達. 実験医学 (増刊 情報伝達研究の新しい展開) 11, 191-196 (1993)
 
金保安則, 加納宏行, 小池晃彦, 岡野幸雄, 野澤義則:ホスホリパーゼ D の活性化機構. 実験医学 (増刊 情報伝達研究の新しい展開) 11, 31-37 (1993)
 
中島 茂, 坂野喜子, 野澤義則:細胞内情報伝達の分子メカニズム. 呼吸 13, 719-727 (1994)
 
中島 茂, 野澤義則, 工藤修三:イノシトール. 日本臨床 (広範囲血液・尿化学検査・免疫学的検査) 683, 738-741 (1995)
 
中島 茂, 野澤義則:フォスホリパーゼ D の細胞増殖制御における役割. 医学のあゆみ 173, 182-123 (1995)
 
中島 茂, 坂野喜子, 野澤義則:細胞活動におけるホスホリパーゼ D の役割と活性調節機構. 蛋白質 核酸 酵素 40, 877-888 (1995)
 
永田浩一, 野澤義則:GTPase スーパーファミリー. 特集:遺伝子・タンパク質のファミリー・スーパーファミリー. 生体の科学 46, 581-583 (1995)
 
中島 茂, 野澤義則:好中球活性化とカルシウム. 特集:アレルギーとカルシウム. CLINICAL CALCIUM 5, 22-26 (1995)
 
野澤義則, 大木和夫:生体膜脂質の動的構造と情報変換. 特集:脂質工学ー現状と未来. 油化学 44, 721-724 (1995)
 
野澤義則:脂質と情報伝達. 特集:脂質 再発見−注目される脂質の新しい機能. 細胞工学 14, 1255-1263 (1995)
 
中島 茂:血小板活性化と膜リン脂質代謝. 血栓止血誌 7, 2-10 (1996)
 
野澤義則:コレステロールと生体膜. 特集:Up Date コレステロールのすべて−基礎と臨床−. 現代医療 28, 21-24 (1996)
 
野澤義則:Rab と血小板. 実験医学 (増刊 GTP 結合蛋白質) 14, 242-243 (1996)
 
野澤義則, 岩崎愛彦, 中島 茂:信号伝達と細胞の最終分化−ケラチノサイト. 特集:細胞分化. 生体の科学 47, 220-225 (1996)
 
大口健司, 野澤義則:ホスホリパーゼ D(PLD) 活性調節と低分子量 GTP 結合蛋白質. 特集:膜脂質シグナリングの最新動向. 膜 21, 177-183 (1996)
 
野澤義則:イノシトールリン脂質情報伝達. 実験医学 (増刊 シグナリングと脂質) 14, 18-22 (1996)
 
坂野喜子, 野澤義則:ホスホリパーゼ C の多様性. 実験医学 (増刊 シグナリングと脂質) 14, 86-92 (1996)
 
中島 茂, 坂野喜子, 野澤義則:血小板活性化における膜脂質シグナリング. 特集:分泌異常による先天性凝固線溶因子欠乏症. 血液・腫瘍科, 印刷中
 
中島 茂, 坂野喜子, 野澤義則:血小板膜脂質と情報伝達. 特集:血小板機能とその新しい展開. 細胞,印刷中
 
総説 (欧文・国外)
Nagata K, Nozawa Y: GTP-binding proteins in human platelets, Trends in Comp Biochem Physiol 1, 463-482 (1993)
 
Noda M, Okano Y, Nozawa Y, Egorova A, Higashida H: Endothelin induces phosphoinositide metabolite-dependent cellular responses in NG108-15 hybrid cells, Ann New York Acad Sci 707, 482-485 (1993)
 
Boyle SM, Szaniszlo PJ, Nozawa Y, Jacobson ES, Cole GT: Potential molecular targets of metabolic pathways, J Med Vet Mycol 32, 79-89 (1994)
 
原著 (和文)
熊田貴彦, 藤宮 大, 宮田英雄, 坂野喜子, 野沢義則:ラット好塩基球性白血病 (RBL-2H3) 細胞の抗原刺激および Ca 2+ イオノフォア刺激によるセロトニン分泌応答と蛋白質チロシンリン酸化. アレルギー 42, 64-72 (1993)
 
川村廣美, 北川 章, 河合 清, 森 悟, 野澤義則:血清アルブミンとの相互作用に関する分光蛍光学的研究. マイコトキシン 39, 13-18 (1994)
 
井上稲子, ファリバ ミルボド, 清島真理子, 森 俊二, 野澤義則:Cryptococcus neoformans の増殖過程における脂質生合成に関する研究. 真菌誌 35, 421-425 (1994)
 
中村好克, 藤宮 大, 熊田貴彦, 小塩勝博, 宮田英雄, 中島 茂, 野澤義則:ラット好塩基球性白血病 (RBL-2H3) 細胞の抗原刺激によるホスホリパーゼD活性化に対する Pemirolast Potassium の効果. アレルギー 44, 624-629 (1995)
 
小塩勝博, 中村好克, 宮田英雄, 坂野喜子, 中島 茂, 野澤義則:ラット好塩基球性白血病 (RBL-2H3) 細胞のホスホリパーゼ D の活性化及び分泌応答におけるプロテインキナーゼ C アイソザイムの関与. アレルギー 44, 1410-1417 (1995)

加藤幸弘, 坂野喜子, 中島 茂, 岡 伸光:骨芽細胞様細胞 MC3T3-E1 の分化初期応答におけるプロスタグランディン F 2α の作用−β-グリセロリン酸とアスコルビン酸による分化誘導. 口科誌, 45, 1-12 (1996)
 
原著 (欧文・国内)
Suzuki N, Matsunaga T, Kanaho Y, Nozawa Y: The mechanism of bradykinin-induced arachidonic acid release in osteoblast-like MC3T3-E1 cells: Phospholipase A 2 activation by bradykinin and its regulation by protein kinase C and calcium. J Jpn Orthop Assoc 67, 935-943 (1993)
 
Liu B, Nakashima S, Kanoh H, Takano T, Shimizu T, Nozawa Y: Activation of phospholipase D in Chinese hamster ovary cells expressing platelet-activating factor receptor. J Biochem 116, 882-891 (1994)
 
Kawai K, Kitagawa A, Nakamura T, Nozawa Y: Biological activities of naphthoquinone pigment xanthomegnin from dermatophytes. Proc Jpn Soc Animal Biochem 31, 29-36 (1994)
 
Fujimiya H, Nakashima S, Kumada T, Nakamura Y, Miyata H, Nozawa Y: An antiallergic drug, pemirolast potassium, inhibits inositol 1,4,5-trisphosphate production and Ca 2+ mobilization in antigen-stimulated rat basophilic leukemia (RBL-2H3) cells. Jpn J Allergol 43, 142-151 (1994)
 
Nakamura Y, Nakashima S, Fujimiya H, Kumada T, Kato Y, Miyata H, Nozawa Y: Effect of an antiallergic drug, pemirolast potassium on tyrosine phosphorylation and MAP kinase activation in antigen-stimulated rat basophilic leukemia (RBL-2H3) cells. Jpn J Allergol 44, 34-44 (1995)
 
Mirbod F, Nakashima S, Mori S, Kitajima Y, Nozawa Y: Phospholipid biosynthesis in growing and non-growing conditions in Candida albicans. Jpn J Med Mycol 36, 53-59 (1995)
 
Yano K, Kanoh H, Nakashima T, Sakai N, Yamada H, Nozawa Y: Activation of phosphoinositide-specific phospholipase C by transferrin in porcine cerebral arterial smooth muscle cells. Neurol Med Chir 35, 205-208 (1995)
 
原著 (欧文・国外)
Toth S, Fu T, Nozawa Y, Casaba G: The effect of epinephrine on the intracellular free calcium of parent and Ki-ras-transfected cell. Biochem Biophys Res Commun 190, 353-361 (1993)
 
Yada Y, Polakowska RR, Okano Y, Nozawa Y: Protein kinase C-dependent expression of type I transglutaminase mRNA in ganglioside GQ1b- and calcium-stimulated human keratinocytes. Biochem Biophys Res Commun 190, 688-694 (1993)
 
Okano Y, Mizuno K, Osada S, Nakamura T, Nozawa Y: Tyrosine phosphorylation of phospholipase Cγ in c-met/HGF receptor-stimulated hepatocytes: Comparison with HepG2 hepatocarcinoma cells. Biochem Biophys Res Commun 190, 842-848 (1993)
 
Takenaka K, Kishino J, Arita H, Okano Y, Sakai N, Yamada H, Nozawa Y: Biological activity of the endothelin family in cultured basilar arterial smooth muscle cell. Neurol Res 15, 29-32 (1993)
 
Zhang W, Hara A, Sakai N, Andoh T, Yamada H, Nozawa Y: Radiosensitization and inhibition of deoxyribonucleic acid repair in rat glioma cells by long-term treatment with 12-0-tetradecanoyl-phorbol 13-acetate. Neurosurgery 32, 432-437 (1993)
 
Zhang W, Yamada H, Sakai N, Nozawa Y: Sensitization of C6 glioma cells to radiation by staurosporine, a potent protein kinase C inhibitor. J Neuro Oncol 15, 1-7 (1993)
 
Kumada T, Miyata H, Nozawa Y: Involvement of tyrosine phospholylation in IgE receptor-mediated phospholipase D activation in rat basophilic leukemia (RBL-2H3) cells. Biochem Biophys Res Commun 191, 1363-1368 (1993)
 
Nakashima T, Takenaka K, Nisimura Y, Andoh T, Sakai N , Yamada H , Banno Y, Okano Y, Nozawa Y: Phospholipase C activity in cerebrospinal fluid following subarachnoid hemorrhage related to brain damage. J Cereb Blood Flow Metab 13, 255-259 (1993)
 
Kanoh H, Kanaho Y, Nozawa Y: Requirement of adenosine 5'-triphosphate and Ca 2+ for guanosine 5'-triphosphate-binding protein-mediated phospholipase D activation in rat pheochromocytoma PC12 cells. Neurosci Lett 151, 146-149 (1993)
 
Kanaho Y, Nakai Y, Katoh M, Nozawa Y: The phosphatase inhibitor 2,3- diphosphoglycerate interferes with phospholipase D activation in rabbit peritoneal neutrophil. J Biol Chem 170, 12492-12497 (1993)
 
Banno Y, Sakai T, Kumada T, Nozawa Y: Potentiation by cholera toxin of bradykinin-induced inositol phosphate production in the osteoblast-like cell line MC3T3-E1. Biochem J 292, 401-408 (1993)
 
Koike T, Hirai K, Morita T, Nozawa Y: Stem cell factor-induced signal transduction in rat mast cells. J Immunol 151, 359-366 (1993)
 
Nagata K, Okano Y, Nozawa Y: Evidence for presence of a low Mr GTP-binding protein, ram p25, in human platelet membranes. Platelets 4, 268-274 (1993)
 
Banno Y, Okano Y, Furukawa K, Tiedtke A, Kobata A, Nozawa Y: Processing and secretion of lysosomal acid α-glucosidase in Tetrahymena wild type and secretion-deficient mutant cells. J Euk Microbiol 40, 515-520 (1993)
 
Nagata K, Nozawa Y: Subcellular localization of a low Mr GTP-binding protein, c25KG, in resting and stimulated human platelets. Biochem Biophys Res Commun 195, 1081-1088 (1993)
 
Hashii M, Nozawa Y, Higashida H: Bradykinin-induced cytosolic Ca 2+ oscillations and inositol tetrakisphospate-induced Ca 2+ influx in voltage-clamped ras-transformed NIH/3 T3 fibroblasts: J Biol Chem 268, 19403-19410 (1993)
 
Kida N, Yoshimura T, Takahashi H, Nagao S, Nozawa Y, Furukawa Y, Mori K, Hayashi K: Estrogen-inducible pS2 protein is not the key regulatory component in the proliferation of human breast cancer cells (MCF-7): Eur J Biochem 215, 671-676 (1993)
 
Mirbod F, Mori S, Nozawa Y: Methods for phospholipid extraction in Candida albicans: an extraction method with high efficacy. J Med Veter Mycol 31, 405-409 (1993)
 
Seishima M, Takagi H, Okano Y, Mori S, Nozawa Y: Ganglioside-induced terminal differentiation of human keratinocytes: early biochemical events in signal transduction. Arch Dermatol Res 285, 397-401 (1993)
 
Mori S, Kawai K, Nozawa Y, Koyama K, Natori S: The impairing effects of chaetochromin D on mitochondrial respiration and structure. Mycotoxin Res 9, 85-93 (1993)
 
Koike T, Mizutani T, Hirai K, Morita Y, Nozawa Y: SCF/c-KIT receptor-mediated arachidonic acid liberation in rat mast cells. Biochem Biophys Res Commun 197, 1570-1577 (1993)
 
Alam S, Banno Y, Nozawa Y: Purification and characterization of phospholipase C preferentially hydrolysing phosphatidylcholine in Tetrahymena membranes. J Euk Microbiol 40, 775-781 (1993)
 
Ozeki T, Osada K, Seishima M, Mori S, Nozawa Y: Decreased bradykinin binding sites in fibroblasts from progressive systemic scleroderma. Arch Dermatol Res 286, 133-136 (1994)
 
Banno Y, Okano Y, Nozawa Y: Thrombin-mediated phosphoinositide hydrolysis in Chinese hamster ovary cells overexpressing phospholipase C-δ1. J Biol Chem 269, 15846- 15852 (1994)
 
Nagata K, Takemasa T, Alam S, Hattori T, Watanabe Y, Nozawa Y: Cloning of cDNAs encoding a cell-cycle-regulatory GTP-binding low-Mr (GBLM) protein, Ran/TC4, from micronucleated Tetrahymena thermophila and amicronuclealted Tetrahymena pyriformis. Gene 144, 123-125 (1994)
 
Nakashima S, Chatani Y, Nakamura M, Miyoshi N, Kohno M, Nozawa Y: Tyrosine phosphorylation and activation of mitogen-activated protein kinases by thrombin in human platelets: possible involvement in late arachidonic acid release. Biochem Biophys Res Commun 198, 497-503 (1994)
 
Sugiyama T, Sakai T, Nozawa Y, Oka N: Prostaglandin F 2α-stimulated phospholipase D activation in osteoblast-like MC3T3-E1 cells : involvement in sustained 1,2-diacylglycerol production. Biochem J 298, 479-484 (1994)
 
Osada S, Okano Y, Saji S, Nozawa Y: Spontaneous Ca 2+ release from a caffeine and ryanodine-sensitive intracellular Ca 2+ store in freshly prepared hepatocytes. Hepatology 19, 514-517 (1994)
 
Banno Y, Asano T, Nozawa Y: Proteolytic modification of membrane-associated phospholipase C-β by μ-calpain enhances its activation by G-protein βγ subunits in human platelets. FEBS Lett 340, 185-188 (1994)
 
Hashii M, Hirata M, Ozaki S, Nozawa Y, Higashida H: Ca 2+ influx evoked by inositol-3,4,5,6-tetrakisphosphate in ras-transformed NIH/3T3 fibroblasts. FEBS Lett 340, 276-280 (1994)
 
Inazu A, Sato K, Nakayama T, Deyashiki Y, Hara A, Nozawa Y: Purification and characterization of a novel dimeric 20α-hydroxysteroid dehydrogenase from Tetrahymena pyriformis. Biochem J 297, 195-200 (1994)
 
Kumada T, Nakashima S, Miyata H, Nozawa Y: Potent activation of phospholipase D by phenylarsine oxide in rat basophilic leukemia (RBL-2H3) cells. Biochem Biophys Res Commun 199, 792-798 (1994)
 
Hashii M, Hirata M, Ozeki S, Nozawa Y, Higashida H: Ca 2+ influx gated by inositol-3,4,5,6-tetrakisphosphate in NIH/3T3 fibroblasts. Biochem Biophys Res Commun 200, 1300-1306 (1994)
 
Kameyama Y, Nagata K, Mizuno-Kamiya M, Yokota Y, Fujita A, Nozawa Y: Localization of a low Mr GTP-binding protein, rap1 protein, in plasma membranes and secretory granule membranes of rat parotid gland. Life Sci 55, 213-219 (1994)
 
Kumada T, Banno Y, Miyata H, Nozawa Y: Phosphoinositide hydrolysis in Ki-ras-transformed fibroblasts stimulated by platelet-derived growth factor and bradykinin. Int J Biochem 26, 1049-1054 (1994)
 
Suzuki T, Nakashima S, Nozawa Y: Inhibition of phosphatidylinositol 4-phosphate 5-kinase by cyclic AMP in human platelets. Platelets 5, 258-265 (1994)
 
Suzuki T, Nakashima S, Nozawa Y: Regulation of phosphatidylinositol 4-phosphate 5-kinase by protein kinase C in human platelet membranes. Platelets 5, 336-342 (1994)
 
Nagata K, Nozawa Y: Haemoglobin inhibits GTP-hydrolysis and GDP/GTP-exchange activities of a low Mr GTP-binding protein, ras p21. Br J Haematol 88, 706-711 (1994)
 
Yoshimi N, Wang A, Makita H, Suzuki M, Okano Y, Banno Y, Nozawa Y, Mori H: Reduced expression of phospholipase C-δ, a signal transducing enzyme, in rat colon neoplasms induced by methylazoxymethanol acetate. Mol Carcinogenesis 11, 192-196 (1994)
 
Alam S, Banno Y, Nakashima S, Nozawa Y: Defective phospholipase D activation in Ki-ras-transformed NIH3T3 cells : Evidence for downstream of PLC-γ1 in PDGF-mediated signal transduction. Biochem Biophys Res Commun 207, 460-466 (1995)
 
Banno Y, Nakahima S, Hachiya T, Nozawa Y: Endogeneous cleavage of phospholipase Cβ-3 by agonist-induced activation of calpain in human platelets. J Biol Chem 270, 4318-4324 (1995)
 
Takemura OS, Iinuma M, Tosa H, Miguel OG, Moreira EA, Nozawa Y: A flavone from leaves of Arrabidea chica f. cuprea. Phytochemistry 38, 1299-1300 (1995)
 
Aoyama Y, Seishima M, Mori S, Kitajima Y, Okano Y, Nozawa Y: Involvement of protein kinase C in bradykinin-induced intracellular calcium increase in primary cultured human keratinocytes. J Dermatol Sci 9, 111-116 (1995)
 
Nagata K, Nozawa Y: A low Mr GTP-binding protein, Rap1, in human platelets: localization, translocation and phosphorylation by cyclic AMP-dependent protein kinase. Br J Haematol 90, 180-186 (1995)
 
Ibrahim AS, Mirbod F, Filler SG, Banno Y, Cole GT, Kitajima Y, Edwords JE, Nozawa Y,
Ghannoum MA: Evidence implying phospholipase as a virulence factor of Candida albicans. Infect Immun 63, 1993-1998 (1995)
 
Fujita H, Lahman L, Janmey PA, Kwiakowski DJ, Stossel TP, Banno Y, Nozawa Y, Muller L, Ishizaki A, Kuzumaki N: Functions of [His 321] gelsolin isolated from a flat revertant of ras-transformed cells. Eur J Biochem 229, 615-620 (1995)
 
Seishima M, Aoyama Y, Mori S, Nozawa Y: Involvement of phospholipase D in ganglioside GQ1b-induced biphasic production of diacylglycerol in human keratinocytes. J Invest Dermatol 104, 835-838 (1995)
 
Ohguchi K, Banno Y, Nakashima S, Nozawa Y: Activation of membrane-bound phospholipase D by protein kinase C in HL60 cells: Synergistic action of a small GTP-binding protein RhoA. Biochem Biophys Res Commun 211, 306-311 (1995)
 
Nakashima S, Banno Y, Watanabe T, Nakamura Y, Mizutani T, Sakai H, Zhao Y, Sugimoto Y, Nozawa Y: Depletion and site-directed mutagenesis of EF-hand domain of phospholipase-Cδ1: Effects of its activity. Biochem Biophys Res Commun 211, 364-369 (1995)
 
Mirbod F, Banno Y, Ghannoum MA, Ibrahim AS, Nakashima S, Kitajima Y, Cole GT, Nozawa Y: Purification and characterization of lysophospholipase-transacylase (h-LPTA) from a highly virulent strain of Candida albicans. Biochim Biophys Acta 1257, 181-189 (1995)
 
Adachi T, Nakashima S, Saji S, Nakamura T, Nozawa Y: Roles of prostaglandin production and mitogen-activated protein kinase activation in hepatocyte growth factor-mediated rat hepatocyte proliferation. Hepatology 21, 1668-1674 (1995)
 
Liu B, Nakashima S, Takano T, Shimizu T, Nozawa Y: Implication of protein kinase Cα in PAF-stimulated phospholipase D activation in Chinese hamster ovary (CHO) cells expressing PAF receptor. Biochem Biophys Res Commun 214, 418-423 (1995)
 
Ishizuka T, Nakashima T, Yamamoto M, Kajita K, Yamada K, Wada H, Itaya S, Yasuda K, Nozawa Y: Effects of wortmannin on glucose uptake and protein kinase C activity in rat adipocytes. Diabetes Res Clin Practice 29, 143-152 (1995)
 
Nagata K, Okano Y, Nozawa Y: Identification of heterotrimeric GTP-binding proteins in human megakaryoblastic leukemia cell line, MEG-01, and their alteration during cellular differentiation. Life Sci 57, 1675-1681 (1995)
 
Kumada T, Nakashima S, Nakamura Y, Miyata H, Nozawa Y: Antigen-mediated phospholipase D activation in rat basophilic leukemia (RBL-2H3) cells: possible involvement of calcium/calmodulin. Biochim Biophys Acta 1258, 107-114 (1995)
 
Yoshimi N, Ino N, Suzui M, Tanaka T, Nakashima S, Nakamura M, Nozawa Y, Mori H: The mRNA overexpression of inflammatory enzymes, phospholipase A 2, cyclooxygenase, in the large bowel mucosa and neoplasms of F344 rats treated with naturally occurring carcinogen, 1-hydroxy-anthraquinone. Cancer Lett 97, 75-82 (1995)
 
Nakashima S, Mizutani T, Nakamura Y, Takemura SO, Nakamura M, Miyata H, Katagiri Y, Nozawa Y: Effects of selective phosphodiesterase type IV inhibitor, rolipram, on signal transducing phospholipases in neutrophil: Inhibition of phospholipases A 2, D but not C. Comp Biochem Physiol 112C, 137-143 (1995)
 
Nagata K, Okano Y, Nozawa Y: Possible interaction of haemoglobin with a low Mr GTP-binding protein, ram p25. Biochem Mol Biol Int 35, 507-515 (1995)
 
Nagata K, Sakagami H, Kondo H, Nozawa Y: Identification and localization of gene expression of a low Mr GTP-binding protein, ram p25 in pituitary gland. Biochem Biophys Res Commun 217, 1223-1230 (1995)
 
Ohguchi K, Banno Y, Nakashima S, Nozawa Y: Regulation of membrane-bound phospholipase D by protein kinase C in HL60 cells. J Biol Chem 271, 4366-4372 (1996)
 
Nakamura Y, Nakashima S, Ojio K, Banno Y, Miyata H, Nozawa Y: C2-ceramide inhibits IgE-mediate phospholipase D but not C activation in rat basophilic leukemia (RBL-2H3) cells. J Immunol 156, 256-262 (1996)
 
Nakashima S, Zhao Y, Nozawa Y: Molecular cloning of △ 9 fatty acid desaturase from protozoan Tetrahymena thermophila and its mRNA expression during thermal membrane adaptation. Biochem J 317, 29-34 (1996)
 
Liu B, Nakashima S, Ito S, Nozawa Y: PLD activation in Chinese hamster ovary (CHO) cells transfected with PGF2α receptor cDNA. Prostaglandins 51, 233-248 (1996)
 
Adachi T, Nakashima S, Saji S, Nakamura T, Nozawa Y: Mitogen-activated protein kinase activation in hepatocyte growth factor-stimulated rat hepatocytes: Involvement of protein tyrosine kinase and protein kinase C. Hepatology 23, 1244-1253 (1996)
 
Kovacs P, Csaba G, Ito Y, Nozawa Y: Phospholipase D activity in the Tetrahymena pyriformis. Biochem Biophys Res Commun 222, 359-361 (1996)
 
Banno Y, Nakashima S, Ohsawa M, Nozawa Y: Differential translocation of phospholipase C isozymes to integrin-mediated cytoskeletal complexes in thrombin-stimulated human platelets. J Biol Chem 271, 14989-14994 (1996)
 
Kumada T, Nakashima S, Nakamura Y, Miyata H, Nozawa Y: Phenylarsine oxide (PAO) -mediated activation of phospholipase D in rat basophilic leukemia (RBL-2H3) cells: Possible involvement of calcium and protein kinase C. Immunobiology 195, 347-359 (1996)
 
Sakai H, Nakashima S, Yoshimura S, Nakatani K, Shinoda J, Sakai N, Yamada H, Nozawa Y: Suppressed expression of CD44 variant isoforms during human glioma A172 cell differentiation induced by cyclic AMP. Neurosci Lett 250, 189-192 (1996)
 
Nakamura Y, Nakashima S, Kumada T, Ojio K, Miyata H, Nozawa Y: Brefeldin A inhibits antigen- or calcium ionophore-stimulated but not PMA-induced phospholipase D activation in rat basophilic leukemia (RBL-2H3) cells. Immunobiology 195, 231-242 (1996)
 
Alam S, Nakashima S, Deyashiki Y, Banno Y, Hara A, Nozawa Y: Molecular cloning of a gene encoding acid α-glucosidase from Tetrahymena pyriformis. J Euk Microbiol 43, 295-303 (1996)
 
Nagata K, Okano Y, Nozawa Y: Protein kinase C isozymes in human megakaryoblastic leukemia cell line, MEG-01: Possible involvement of the isozymes in the differentiation process of MEG-01 cells. Br J Haematol 93, 762-771 (1996)
 
Ojio K, Banno Y, Nakashima S, Kato N, Watanabe K, Lyerly DM, Miyata H, Nozawa Y: Effect of Clostridium difficile toxin B on IgE receptor-mediated signal transduction in rat basophilic leukemia cells: inhibition of phospholipase D activation. Biochem Biophys Res Commun 224, 591-596 (1996)
 
Yoshimura S, Nakashima S, Ohguchi K, Sakai H, Shinoda J, Sakai N, Nozawa Y: Differential mRNA expression of phospholipase D (PLD) isozymes during cAMP-induced differentiation in C6 glioma cells. Biochem Biophys Res Commun 225, 494-499 (1996)
 
Banno Y, Ito Y, Ojio K, Kanoh H, Nakashima S, Nozawa Y: Membrane-associated phospholipase D activity in neural cell line PC12. J Lipid Mediators and Cell Signaling, in press
 
Mirbod F, Nakashima S, Kitajima Y, Ghannoum MA, Cannon RD, Nozawa Y: Molecular cloning of a gene encoding translation initiation factor (TIF) from C. albicans. J Med Vet Mycol, in press
 
Hashii M, Nakashima S, Yokoyama S, Enomoto K, Minabe Y, Nozawa Y, Higashida H: Bradykinin-activated two signal pathways of protein tyrosine phosphorylation and formation of inositol tetrakisphosphates merge at the Ca 2+ influx process in ras-transformed NIH3T3 fibroblast cells. Biochem J, in press
 
Adachi T, Nakashima S, Saji S, Nakamura T, Nozawa Y: Phospholipase D activation in hepatocyte growth factor-stimulated rat hepatocytes; Implication in the expressions of c-jun and c-fos. Hepatology, in press
 
Zhao Y, Nakashima S, Nozawa Y: Molecular cloning of dalta 9 fatty acid desaturase and growth associated changes in its mRNA expression in Tetrahymena pyriformis, Eur J Prositol, in press
 
その他
Nozawa Y, Mirbod F, Banno Y, Ibrahim AS, Nakashima S, Kitajima Y, Cole GT, Ghannoum MA: Lysophospholipase-transacylase as a virulence factor in Candida albicans. Genes and Genomes in Medically Important Fungi, Proceedings of the First International Synposium on Deep Mycoses, (ed Tanaka K, Magee PT, Yamaguchi H), Foundation for Advancement of International Science, 167-173 (1996)
 
Nozawa Y, Nakashima S, Ohguchi K, Banno Y: Membrane lipids and signal transduction. BIO JAPAN'96, in press
 
坂野喜子:低分子量 G 蛋白質の新しい機能−情報変換ホスホリパーゼ D の活性化因子. 蛋白質核酸酵素, フラクションコレクター 40, 1752 (1995)
 
坂野喜子, 中島 茂:G 蛋白質. ホスホリパーゼ C との関係. 現代医療 27, 329-333 (1995)
 
野澤義則:生体膜の非対称性, 相転移温度, 相転移, 相分離, 側方拡散, ダニエリ. ダブリンのモデル, 鞭毛膜. 生化学辞典, 印刷中
 
野澤義則:ホスホリパーゼ C, D, リン酸化−脱リン酸サイクル. 分子細胞生物学辞典, 印刷中